| Time | Status | Match | FT | H1 | Stats |
| 05/03/2022 14:00 |
(FT) | Gudja United[7] Gzira United[5] |
1 2 |
0 2 |
MF | ME |
| 05/03/2022 16:00 |
(FT) | Hibernians FC[2] Balzan[9] |
1 0 |
0 0 |
MF | ME |
| 05/03/2022 18:00 |
(FT) | Mosta[8] Valletta FC[10] |
2 2 |
0 0 |
MF | ME |
| 06/03/2022 14:00 |
(FT) | Santa Lucia[11] Hamrun Spartans[4] |
0 1 |
0 0 |
MF | ME |
| 06/03/2022 14:00 |
(FT) | Sirens[6] Floriana[1] |
0 3 |
0 2 |
MF | ME |
| 06/03/2022 18:00 |
(FT) | Sliema Wanderers FC[12] Birkirkara FC[3] |
0 0 |
0 0 |
MF | ME |