| Time | Status | Match | FT | H1 | Stats |
| 19/02/2022 14:00 |
(FT) | Gudja United[7] Balzan[8] |
1 0 |
1 0 |
MF | ME |
| 19/02/2022 16:00 |
(FT) | Hibernians FC[1] Birkirkara FC[3] |
2 3 |
0 2 |
MF | ME |
| 19/02/2022 18:00 |
(FT) | Sirens[6] Hamrun Spartans[5] |
1 1 |
0 1 |
MF | ME |
| 20/02/2022 11:30 |
(FT) | Mosta[9] Sliema Wanderers FC[11] |
1 0 |
1 0 |
MF | ME |
| 20/02/2022 14:00 |
(FT) | Santa Lucia[12] Valletta FC[10] |
2 1 |
1 0 |
MF | ME |
| 20/02/2022 18:00 |
(FT) | Gzira United[4] Floriana[2] |
1 2 |
0 2 |
MF | ME |