| Time | Status | Match | FT | H1 | Stats |
| 27/11/2021 14:00 |
(FT) | Floriana[2] Sirens[7] |
1 2 |
0 1 |
MF | ME |
| 27/11/2021 16:00 |
(FT) | Birkirkara FC[4] Sliema Wanderers FC[12] |
2 0 |
0 0 |
MF | ME |
| 27/11/2021 18:00 |
(FT) | Valletta FC[5] Mosta[9] |
3 1 |
2 0 |
MF | ME |
| 28/11/2021 14:00 |
(FT) | Gzira United[8] Gudja United[11] |
3 2 |
1 0 |
MF | ME |
| 28/11/2021 16:00 |
(FT) | Hamrun Spartans[6] Santa Lucia[10] |
3 0 |
2 0 |
MF | ME |
| 28/11/2021 18:00 |
(FT) | Balzan[3] Hibernians FC[1] |
1 2 |
1 1 |
MF | ME |