| Time | Status | Match | FT | H1 | Stats |
| 12/02/2022 14:00 |
(FT) | Floriana[2] Mosta[10] |
2 0 |
0 0 |
MF | ME |
| 12/02/2022 16:00 |
(FT) | Valletta FC[9] Hibernians FC[1] |
1 4 |
0 2 |
MF | ME |
| 12/02/2022 18:00 |
(FT) | Balzan[7] Gzira United[6] |
1 3 |
1 1 |
MF | ME |
| 13/02/2022 14:00 |
(FT) | Hamrun Spartans[4] Gudja United[8] |
0 1 |
0 0 |
MF | ME |
| 13/02/2022 16:00 |
(FT) | Sliema Wanderers FC[11] Santa Lucia[12] |
1 1 |
1 1 |
MF | ME |
| 13/02/2022 18:00 |
(FT) | Birkirkara FC[3] Sirens[5] |
1 1 |
1 1 |
MF | ME |