| Time | Status | Match | FT | H1 | Stats |
| 22/01/2022 14:00 |
(FT) | Balzan[6] Hamrun Spartans[3] |
2 2 |
2 0 |
MF | ME |
| 22/01/2022 16:00 |
(FT) | Mosta[11] Hibernians FC[1] |
1 1 |
0 1 |
MF | ME |
| 22/01/2022 18:00 |
(FT) | Gudja United[9] Sliema Wanderers FC[12] |
1 0 |
1 0 |
MF | ME |
| 23/01/2022 14:00 |
(FT) | Gzira United[5] Valletta FC[8] |
1 1 |
0 0 |
MF | ME |
| 23/01/2022 16:00 |
(FT) | Sirens[7] Santa Lucia[10] |
2 1 |
1 1 |
MF | ME |
| 23/01/2022 18:00 |
(FT) | Floriana[2] Birkirkara FC[4] |
1 0 |
1 0 |
MF | ME |