| Time | Status | Match | FT | H1 | Stats |
| 17/09/2021 20:00 |
(FT) | Sparta Rotterdam[14] NEC Nijmegen[6] |
1 1 |
1 1 |
MF | ME |
| 18/09/2021 16:30 |
(FT) | SC Heerenveen[4] Fortuna Sittard[12] |
1 0 |
1 0 |
MF | ME |
| 18/09/2021 18:45 |
(FT) | Willem II[5] Groningen[10] |
2 1 |
2 0 |
MF | ME |
| 18/09/2021 20:00 |
(FT) | Ajax Amsterdam[2] Cambuur Leeuwarden[8] |
9 0 |
4 0 |
MF | ME |
| 18/09/2021 21:00 |
(FT) | Utrecht[3] RKC Waalwijk[11] |
2 2 |
1 2 |
MF | ME |
| 19/09/2021 12:15 |
(FT) | Go Ahead Eagles[16] Zwolle[18] |
1 0 |
0 0 |
MF | ME |
| 19/09/2021 14:30 |
(FT) | PSV Eindhoven[1] Feyenoord Rotterdam[7] |
0 4 |
0 1 |
MF | ME |
| 19/09/2021 16:45 |
(FT) | Heracles Almelo[17] AZ Alkmaar[15] |
3 2 |
1 1 |
MF | ME |
| 19/09/2021 16:45 |
(FT) | Vitesse Arnhem[9] Twente Enschede[13] |
1 4 |
0 2 |
MF | ME |