| Time | Status | Match | FT | H1 | Stats |
| 11/03/2022 20:00 |
(FT) | Cambuur Leeuwarden[8] Ajax Amsterdam[1] |
2 3 |
0 2 |
MF | ME |
| 12/03/2022 16:30 |
(FT) | Sparta Rotterdam[18] Go Ahead Eagles[11] |
1 0 |
0 0 |
MF | ME |
| 12/03/2022 18:45 |
(FT) | Groningen[10] NEC Nijmegen[9] |
4 3 |
2 3 |
MF | ME |
| 12/03/2022 21:00 |
(FT) | RKC Waalwijk[14] SC Heerenveen[13] |
0 0 |
0 0 |
MF | ME |
| 13/03/2022 12:15 |
(FT) | Fortuna Sittard[17] Willem II[15] |
1 0 |
0 0 |
MF | ME |
| 13/03/2022 14:30 |
(FT) | Utrecht[6] PSV Eindhoven[2] |
0 1 |
0 0 |
MF | ME |
| 13/03/2022 14:30 |
(FT) | Heracles Almelo[12] Vitesse Arnhem[7] |
0 0 |
0 0 |
MF | ME |
| 13/03/2022 16:45 |
(FT) | Zwolle[16] Feyenoord Rotterdam[3] |
1 2 |
1 0 |
MF | ME |
| 13/03/2022 20:00 |
(FT) | AZ Alkmaar[4] Twente Enschede[5] |
0 1 |
0 0 |
MF | ME |