| Time | Status | Match | FT | H1 | Stats |
| 27/08/2021 20:45 |
(FT) | Kortrijk[5] KV Mechelen[10] |
2 2 |
0 2 |
MF | ME |
| 28/08/2021 16:15 |
(FT) | Sporting Charleroi[8] Beerschot AC[18] |
5 2 |
1 0 |
MF | ME |
| 28/08/2021 18:30 |
(FT) | Cercle Brugge[12] St-Truidense VV[16] |
0 1 |
0 1 |
MF | ME |
| 28/08/2021 18:30 |
(FT) | AS Eupen[1] Seraing United[11] |
1 2 |
0 0 |
MF | ME |
| 28/08/2021 20:45 |
(FT) | St Gilloise[4] Standard Liege[3] |
4 0 |
2 0 |
MF | ME |
| 29/08/2021 13:30 |
(FT) | Gent[15] Club Brugge[2] |
6 1 |
3 0 |
MF | ME |
| 29/08/2021 16:00 |
(FT) | Royal Antwerp[14] Oud Heverlee[17] |
2 2 |
2 0 |
MF | ME |
| 29/08/2021 18:30 |
(FT) | Genk[7] Anderlecht[9] |
1 0 |
0 0 |
MF | ME |
| 29/08/2021 21:00 |
(FT) | Oostende[6] Zulte-Waregem[13] |
0 2 |
0 1 |
MF | ME |