| Time | Status | Match | FT | H1 | Stats |
| 08/04/2022 21:00 |
(FT) | Sevilla[4] Granada[16] |
4 2 |
1 1 |
MF | ME |
| 09/04/2022 14:00 |
(FT) | Cadiz[17] Real Betis[5] |
1 2 |
0 0 |
MF | ME |
| 09/04/2022 16:15 |
(FT) | Mallorca[18] Atletico Madrid[3] |
1 0 |
0 0 |
MF | ME |
| 09/04/2022 18:30 |
(FT) | Villarreal[7] Athletic Bilbao[8] |
1 1 |
0 1 |
MF | ME |
| 09/04/2022 21:00 |
(FT) | Real Madrid[1] Getafe[14] |
2 0 |
1 0 |
MF | ME |
| 10/04/2022 14:00 |
(FT) | Osasuna[10] Alaves[20] |
1 0 |
0 0 |
MF | ME |
| 10/04/2022 16:15 |
(FT) | Espanyol[12] Celta Vigo[11] |
1 0 |
0 0 |
MF | ME |
| 10/04/2022 18:30 |
(FT) | Elche[15] Real Sociedad[6] |
1 2 |
1 2 |
MF | ME |
| 10/04/2022 21:00 |
(FT) | Levante[19] Barcelona[2] |
2 3 |
0 0 |
MF | ME |
| 11/04/2022 21:00 |
(FT) | Rayo Vallecano[13] Valencia[9] |
1 1 |
0 0 |
MF | ME |