| Time | Status | Match | FT | H1 | Stats |
| 22/10/2021 21:00 |
(FT) | Osasuna[5] Granada[17] |
1 1 |
1 0 |
MF | ME |
| 23/10/2021 14:00 |
(FT) | Valencia[10] Mallorca[13] |
2 2 |
0 2 |
MF | ME |
| 23/10/2021 16:15 |
(FT) | Cadiz[16] Alaves[19] |
0 2 |
0 1 |
MF | ME |
| 23/10/2021 18:30 |
(FT) | Elche[14] Espanyol[11] |
2 2 |
1 0 |
MF | ME |
| 23/10/2021 21:00 |
(FT) | Athletic Bilbao[9] Villarreal[12] |
2 1 |
1 1 |
MF | ME |
| 24/10/2021 14:00 |
(FT) | Sevilla[3] Levante[18] |
5 3 |
3 1 |
MF | ME |
| 24/10/2021 16:15 |
(FT) | Barcelona[7] Real Madrid[2] |
1 2 |
0 1 |
MF | ME |
| 24/10/2021 18:30 |
(FT) | Real Betis[8] Rayo Vallecano[6] |
3 2 |
2 1 |
MF | ME |
| 24/10/2021 21:00 |
(FT) | Atletico Madrid[4] Real Sociedad[1] |
2 2 |
0 1 |
MF | ME |
| 25/10/2021 21:00 |
(FT) | Getafe[20] Celta Vigo[15] |
0 3 |
0 0 |
MF | ME |