| Time | Status | Match | FT | H1 | Stats | |
| 11/05/2022 01:00 |
(FT) | Orlando City[MLS-4] Philadelphia Union[MLS-2] |
2 1 |
0 0 |
MF | ME | |
| 11/05/2022 01:30 |
(FT) | Washington DC United[MLS-10] New York Red Bulls[MLS-1] |
0 3 |
0 1 |
MF | ME | |
| 11/05/2022 01:30 |
(FT) | Detroit City[USL CH-6] Louisville City[USL CH-1] |
1 1 |
1 1 |
MF | ME | |
| 90 phút [1-1], 120 phút [1-1], Penalty [2-4], Louisville City thắng | ||||||
| 11/05/2022 02:30 |
(FT) | Sporting Kansas City[MLS-11] Dallas[MLS-3] |
2 2 |
0 2 |
MF | ME | |
| 90 phút [2-2], 120 phút [4-2], Sporting Kansas City thắng | ||||||
| 11/05/2022 04:30 |
(FT) | Los Angeles FC[MLS-1] Portland Timbers[MLS-10] |
2 0 |
1 0 |
MF | ME | |
| 12/05/2022 00:30 |
(FT) | Richmond Kickers Charlotte Eagles[MLS-9] |
1 5 |
0 1 |
MF | ME | |
| 12/05/2022 01:00 |
(FT) | New England Revolution[MLS-11] Cincinnati[MLS-5] |
5 1 |
2 1 |
MF | ME | |
| 12/05/2022 01:00 |
(FT) | New York City Fc[MLS-6] Rochester Rhinos |
3 1 |
2 1 |
MF | ME | |
| 12/05/2022 02:00 |
(FT) | Nashville Sc[MLS-9] Atlanta United[MLS-7] |
2 2 |
0 2 |
MF | ME | |
| 90 phút [2-2], 120 phút [3-2], Nashville Sc thắng | ||||||
| 12/05/2022 02:30 |
(FT) | Houston Dynamo[MLS-8] San Antonio[USL CH-3] |
1 0 |
0 0 |
MF | ME | |
| 12/05/2022 04:00 |
(FT) | Seattle Sounders[MLS-12] San Jose Earthquakes[MLS-13] |
2 2 |
0 1 |
MF | ME | |
| 90 phút [2-2], 120 phút [2-2], Penalty [9-10], San Jose Earthquakes thắng | ||||||
| 12/05/2022 04:30 |
(FT) | Sacramento Republic Fc[USL CH-13] Phoenix Rising Arizona U[USL CH-8] |
2 0 |
1 0 |
MF | ME | |
| 12/05/2022 20:00 |
(FT) | Minnesota United[MLS-6] Colorado Rapids[MLS-7] |
2 1 |
1 1 |
MF | ME | |