| Time | Status | Match | FT | H1 | Stats |
| 05/02/2022 14:00 |
(FT) | Mosta[10] Santa Lucia[12] |
1 0 |
1 0 |
MF | ME |
| 05/02/2022 16:00 |
(FT) | Gzira United[6] Hamrun Spartans[3] |
4 1 |
0 0 |
MF | ME |
| 05/02/2022 18:00 |
(FT) | Hibernians FC[1] Sliema Wanderers FC[11] |
1 0 |
1 0 |
MF | ME |
| 06/02/2022 11:30 |
(FT) | Floriana[2] Balzan[7] |
2 1 |
1 0 |
MF | ME |
| 06/02/2022 14:00 |
(FT) | Gudja United[8] Birkirkara FC[4] |
0 1 |
0 1 |
MF | ME |
| 06/02/2022 18:00 |
(FT) | Sirens[5] Valletta FC[9] |
2 1 |
2 1 |
MF | ME |