| Minute | Score | Mainz 05 | Bayer Leverkusen | |
| 15' | 0 - 1 |  Son Heung-Min (Calhanoglu H.) |
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| 28' | 0 - 1 |  Wendell |
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| 34' | 0 - 1 | Jedvaj T. |
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| 46' | 0 - 1 |  Rolfes S. (Bellarabi K.) |
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| 59' | 0 - 2 | Kießling S. (Hilbert R.) |
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| 66' | 0 - 2 | Soto E. (De Blasis P.) |
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| 70' | 0 - 2 | Soto E. |
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| 73' | 0 - 3 | Calhanoglu H. |
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| 78' | 1 - 3 | Soto E. (Penalty) |
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| 79' | 1 - 3 | Drmić J. (Kießling S.) |
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| 81' | 1 - 3 | Samperio J. (Baumgartlinger J.) |
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| 86' | 1 - 3 | Brandt J. (Calhanoglu H.) |
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| 89' | 1 - 3 | Bengtsson P. (Malli Y.) |
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| 90' | 2 - 3 | Soto E. (Penalta) |
