| Time | Status | Match | FT | H1 | Stats |
| 15/10/2021 21:00 |
(FT) | Eibar[5] Almeria[1] |
1 0 |
1 0 |
MF | ME |
| 16/10/2021 16:00 |
(FT) | Girona[20] SD Huesca[12] |
1 3 |
0 0 |
MF | ME |
| 16/10/2021 16:00 |
(FT) | SD Amorebieta[21] Cartagena[10] |
2 3 |
1 1 |
MF | ME |
| 16/10/2021 18:15 |
(FT) | Las Palmas[6] Tenerife[4] |
2 1 |
1 0 |
MF | ME |
| 16/10/2021 20:30 |
(FT) | Malaga[11] Zaragoza[19] |
1 1 |
1 1 |
MF | ME |
| 16/10/2021 21:00 |
(FT) | Sporting de Gijon[2] Alcorcon[22] |
1 0 |
0 0 |
MF | ME |
| 17/10/2021 14:00 |
(FT) | Ud Ibiza[15] CD Mirandes[13] |
0 2 |
0 1 |
MF | ME |
| 17/10/2021 16:00 |
(FT) | Leganes[18] Valladolid[9] |
0 2 |
0 1 |
MF | ME |
| 17/10/2021 18:15 |
(FT) | Real Sociedad B[16] Real Oviedo[8] |
1 1 |
0 0 |
MF | ME |
| 17/10/2021 18:15 |
(FT) | Burgos CF[17] CD Lugo[14] |
1 1 |
1 1 |
MF | ME |
| 17/10/2021 21:00 |
(FT) | SD Ponferradina[3] Fuenlabrada[7] |
0 0 |
0 0 |
MF | ME |