| Time | Status | Match | FT | H1 | Stats |
| 01/10/2022 15:00 |
(FT) | Hamrun Spartans[2] Floriana[6] |
2 0 |
1 0 |
MF | ME |
| 01/10/2022 15:00 |
(FT) | Mosta[7] Sirens[11] |
1 1 |
1 1 |
MF | ME |
| 01/10/2022 17:15 |
(FT) | Santa Lucia[13] Gudja United[3] |
1 3 |
0 1 |
MF | ME |
| 01/10/2022 17:15 |
(FT) | Zebbug Rangers[10] Marsaxlokk[12] |
0 3 |
0 2 |
MF | ME |
| 02/10/2022 15:00 |
(FT) | Birkirkara FC[1] Valletta FC[8] |
3 0 |
1 0 |
MF | ME |
| 02/10/2022 16:00 |
(FT) | Gzira United[5] Pieta Hotspurs[14] |
4 0 |
1 0 |
MF | ME |
| 02/10/2022 17:15 |
(FT) | Balzan[4] Hibernians FC[9] |
0 2 |
0 2 |
MF | ME |