| Time | Status | Match | FT | H1 | Stats |
| 09/10/2021 16:00 |
(FT) | Atherton Collieries[15] Matlock Town[1] |
2 1 |
1 0 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Fc United Of Manchester[10] Nantwich Town[14] |
0 2 |
0 0 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Gainsborough Trinity[13] Ashton United[22] |
1 1 |
1 0 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Grantham Town[21] Bamber Bridge[4] |
1 2 |
0 1 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Hyde United[16] Lancaster City[11] |
0 1 |
0 0 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Mickleover Sports[17] Morpeth Town[19] |
0 4 |
0 3 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Radcliffe Borough[20] Buxton FC[3] |
2 3 |
1 2 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | South Shields[2] Basford Utd[9] |
0 1 |
0 1 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Stafford Rangers[8] Scarborough[12] |
0 1 |
0 0 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Warrington Town AFC[7] Stalybridge Celtic[6] |
3 0 |
1 0 |
MF | ME |
| 09/10/2021 16:00 |
(FT) | Whitby Town[5] Witton Albion[18] |
0 1 |
0 1 |
MF | ME |