| Time | Status | Match | FT | H1 | Stats |
| 19/11/2021 20:45 |
(FT) | KV Mechelen[5] Club Brugge[3] |
2 1 |
0 0 |
MF | ME |
| 20/11/2021 16:15 |
(FT) | Cercle Brugge[17] Sporting Charleroi[4] |
1 2 |
0 2 |
MF | ME |
| 20/11/2021 18:30 |
(FT) | Zulte-Waregem[15] Gent[10] |
1 2 |
0 0 |
MF | ME |
| 20/11/2021 18:30 |
(FT) | Oud Heverlee[12] Seraing United[16] |
1 3 |
0 1 |
MF | ME |
| 20/11/2021 20:45 |
(FT) | Standard Liege[14] AS Eupen[8] |
1 0 |
1 0 |
MF | ME |
| 21/11/2021 13:30 |
(FT) | Anderlecht[6] Kortrijk[9] |
1 1 |
0 1 |
MF | ME |
| 21/11/2021 16:00 |
(FT) | St-Truidense VV[11] Royal Antwerp[2] |
2 1 |
2 0 |
MF | ME |
| 21/11/2021 18:30 |
(FT) | Oostende[13] St Gilloise[1] |
1 7 |
1 4 |
MF | ME |
| 21/11/2021 21:00 |
(FT) | Beerschot AC[18] Genk[7] |
2 0 |
1 0 |
MF | ME |